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This approach measures correlations between the macroscopic outputs we want to model with the cell culture parameters, i.e., the macroscopic inputs, under different experimental conditions.
If microvilli generated identical bumps with everything else being equal, then for the same slowly changing light input, two macroscopic outputs, one integrated from small and the other from large bumps, have the same rate of information transfer (simulated LICs: Figures S4A S4D).
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Conversely, the response form the cellular computation is amplified to yield a macroscopic output action in the environment mediated through the robot's actuators.
To fill the gap, what is critically needed is geometrical information about physical tissue deformation, that is, the macroscopic output of morphogenesis, which can be obtained only by constructing a quantitative tissue deformation map.
Many copolymerization mathematical models can do a sufficiently good job for several macroscopic reactor outputs, but how about predicting microstructural properties reliably?
Soil structure and interactions between biotic and abiotic processes are increasingly recognized as important for explaining the large uncertainties in the outputs of macroscopic SOM decomposition models.
An explicit expression for the time-varying output formation reference function is derived to describe the macroscopic movement of the whole output formation-containment.
The goal of generating a model that accurately describes the output processes at a macroscopic level necessitates the further inclusion of all other processes that are process observable.
In this review, we will present different types of models used in previous work to model the metabolism of suspension cells at the macroscopic level, i.e., to model extracellular outputs as function of extracellular inputs.
The two statistical methods presented above can help to structure problems, to reduce the dimensionality of the problem, to select relevant input and output parameters, and to develop a macroscopic stoichiometric model.
The conversion of MD simulation outputs like atomic positions and velocities to macroscopic observables such thermodynamical and dynamical data requires statistical mechanics [9, 10].
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