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We found no gross macroscopic alterations in the organization of the dorsal horn of Eif4ebp1 -/- mice.
The exclusivity of these polymers lies in their nonlinear response triggered by a very small stimulus and which produces a noticeable macroscopic alterations in their structure.
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These polymers exhibit a non-linear response to a small stimulus leading to a macroscopic alteration in their structure/properties.
In this study, the macroscopic alterations were observed in both groups; however, they were more evident in the copaiba group for all of the times analyzed, showing that oleoresin when in contact with the pleural surface causes a greater pleural reaction than that induced by silver nitrate.
No macroscopic alterations were detected in the remaining 11 inoculated birds, the sentinel bird, or the 9 control birds.
In another experimental study, in which copaiba oil was instilled in the peritoneal cavity, the macroscopic alterations observed were similar to those found in the pleura, thus showing that copaiba oleoresin triggers aggression in the serosa with a corresponding formation of adherences in the process to repair the injury [ 27].
In conclusion, this study has shown that intrapleural injection of copaiba oil and 0.5% silver nitrate produced pleurodesis; however, the macroscopic alterations and acute inflammation were more evident in the copaiba oil group.
The value of macroscopic alterations grade and acute inflammatory reaction grade means was higher in the 24 h copaiba group in relation to silver nitrate.
Macroscopic alterations can be noticed on cut surfaces of the brainstem, where neuronal loss can be inferred from a reduction of neuromelanin pigmentation in the substantia nigra and locus coeruleus.
The tissue macroscopic alterations were also analyzed.
Köberle (1968) suggested that neuron loss in the chronic phase of Chagas' disease is a continuous process lasting decades and that functional disturbances, i.e. discomfort of patients related to impaired gut motility, precede manifest macroscopic alterations, e.g. megacolon.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com