Sentence examples for macro domain of from inspiring English sources

The slightly higher binding affinity of ADP-ribose toward the nsP3 macro domain of VEEV, as predicted by the simulation results, is in good agreement with previous experimental data.

One reasonable possibility is that the antibody cross-reacts with a macro domain of another protein.

We considered the possibility that the antibody developed against macroH2A1 could cross react with the macro domain of macroH2A2 and that macroH2A2 was responsible for the centrosomal staining (although the macroH2A1-NHR antibody does not recognize macroH2A2 in western blots).

Moreover, this interaction appears to be mediated primarily by the macro domain of LRP16 and a specific region of the Rel homology domain (RHD) harboring in p65 rather than in p50 and c-Rel.

It was reported that for cleavage to occur the N-terminus of nsP2 was required as well as the macro domain of nsP3, consisting of 170 N-terminal amino acids [ 38].

The macro domain alone of LRP16 is enough to mediate its interaction with both p65 and AR.

They do not correspond either to the macro-domain of 1 or 2 Mb proposed by Niki et al [ 2] and by Valens et al [ 5].

Being a special member of macro domain proteins, LRP16 was previously identified as a coactivator of both estrogen receptor and androgen receptor, and as an interactor of NF-κB coactivator UXT.

The macro domain is also capable of blocking the chromatin remodeling process mediated by SWI/SNF and ACF [ 5, 6].

Interestingly, all four enzymes are members of the PARP family (see 1), and in particular, PARP9, PARP14 and PARP15 form the group of macro domain containing PARPs.

Chd1l localization to sites of induced DNA damage is dependent on a functional macro domain, and dissociation from sites of damage is dependent on a functional ATPase domain (Ahel et al., 2009; Gottschalk et al., 2009).