As a result, industrial development has been considerable: engineering products manufactured in the city have included buses, agricultural machinery, loading machinery, bicycles, and television sets; there are also consumer goods and foodstuffs industries.
Moreover, under specific conditions that evoke danger signals, peptides from self-antigen can be processed by the antigen-presenting cellular machinery, loaded onto the major histocompatibility antigen groove to serve as targets for immune intervention.
Heavy machinery loaded thousands of ducks into the temporary "Lake Glendale" for each heat of the day Saturday, manned by Kiwanis volunteers and the Glendale Fire Department.
Mariners also risk injury or death from falling overboard and from hazards associated with working with machinery, heavy loads, and dangerous cargo.
It then began the fitting-out phase, as machinery was loaded into the ship and interior work began.
Most peptide epitopes are derived from proteins that are synthesized in the cell, digested by antigen-processing machinery and loaded into the peptide-binding groove.
Mimics are artificial small nucleotide sequences, similar to pre-miRNAS, which are recognized by the miRNA biogenesis machinery or loaded into the RISC, acting as the endogenous miRNA of interest and blocking gene expression [ 58, 61– 63].
In other words instead of delivering exogenous antigen to the canonical site of class I MHC loading, the loading machinery, including class I MHC and TAP transporters is delivered to the antigen.
In eukaryotes, replication initiation machineries are loaded onto DNA during the G1-phase of the cell cycle, 'licensing' origins of replication for subsequent replisome assembly in S-phase (Masai et al., 2010; Abbas et al., 2013).
