Exact(3)
Precursor mRNA (pre-mRNA) splicing is a fundamental link between gene expression and the proteome, and deregulation of the splicing machinery is linked to several age-related chronic illnesses4,5.
The bax/bcl2 apoptotic machinery is linked to the intrinsic apoptotic pathway and the overexpression of BAG3 in those experiments may have been sufficient to overcome that degree of caspase activation.
Genetic alterations in splicing machinery is linked to myelodysplasia [ 19].
Similar(57)
It has been suggested that Hfq, RNAse E and degradosome machinery are linked to bacterial cytoskeletal proteins [14], [15], [36].
The functional role of the molecule in this population is obscure as these lymphocytes do not proliferate to stimulation with anti-CD38 (or anti-IgM), reinforcing the hypothesis that the CD38 and IgM signal transduction machineries are linked.
Focal organization of regulatory machinery within the interphase nucleus is linked to biological responsiveness and perturbed in cancer.
The efficiency of the splicing machinery to splice out introns is linked to its ability to recognize and identify exons or introns properly.
However, recent evidence indicates that the core machinery that governs mitochondrial dynamics is linked within complex intracellular signalling cascades, including apoptotic pathways, cell cycle transitions and nuclear factor kappa B activation.
Agricultural machinery is made in Kingaroy, which is linked to Brisbane (100 miles [160 km] southeast) by rail and air and by the Bunya Highway.
How Tim is linked to the apoptotic machinery and the relationship of that connection to ES cell differentiation is not clear.
The Ess1 prolyl isomerase is linked to chromatin remodeling complexes and the general transcription machinery.
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