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The core autophagic machinery is composed of ATG (autophagy-related) protein constituents.
The apoptotic machinery is composed of both upstream regulators and downstream effector components.
We propose that the A-motility machinery is composed of distinct units, with RomR stimulating polyelectrolyte secretion at the lagging pole and AglZ-containing focal adhesion complexes along the cell body.
Virtually all cellular machinery is composed of proteins, whose functions are mediated through biomolecular interactions; these serve to transmit signals and traffic molecular materials throughout the cell, as well as to form larger multimeric complexes capable of more complex behaviour [ 44, 45].
The mitochondrial oxidative phosphorylation (OXPHOS) machinery is composed of four multisubunit respiratory complexes (complex I IV) creating an electrochemical gradient through the coupled transfer of electrons to oxygen and the transport of protons from the matrix across the inner mitochondrial membrane (IMM) into the intermembrane space (IMS), used by the ATP-synthase to produce ATP.
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When k = 3.5, the cluster is further divided to two overlapping sub-clusters which is consistent with the known facts from SGD database that the peroxisomal import machinery are composed of two subcomplexes.
The major antioxidant defense machineries are composed of antioxidant enzymes and biological antioxidants (Itoh et al. 1997; Cho et al. 2006; Riedl et al. 2009).
In yeast, the cleavage/polyadenylation machinery, which is composed of the Cleavage Factor I (CFI) (CSTF in humans) and Cleavage/Polyadenylation Factor (CPF) (CPSF in humans) complexes, is responsible for the recognition of polyA/termination signals and their subsequent processing [2] [6].
Maintenance of muscle mass depends on the integrity of the regenerative machinery, which is composed of SCs and other mononucleated cell types, although, the direct contribution of SCs to myofiber hypertrophy and maintenance remains controversial.
The intracellular machinery of autophagy is composed of a complex of proteins formed by the class III phosphatidylinositol-3-kinase (PI3K), also known as Vps34, and the Bcl-2 interacting BH3 domain protein, Beclin-1 (BECN1).
The core machinery of autophagy is composed of three major functional groups: (i) Atg9 and its cycling system; (ii) a phosphatidylinositol 3-OH kinase (PI3K) complex; and (iii) an ubiquitin-like protein system, which includes two ubiquitin proteins, the Atg12 and Atg8 (mammalian homologue MAP1LC3/LC3) (Mari and Reggiori, 2007).
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