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Modulation of the epigenetic machinery has also been observed in interactions between plants.
There is increasing evidence supporting the ability of nanomaterials to induce DNA damage through the promotion of oxidative stress, although direct interference with DNA and the cell division machinery has also been observed.
In addition to the effect on heterochromatin and centromeres, DNA replication machinery has also been implicated in the epigenetic regulation of open chromatin: in human cells, PCNA was found to target ISWI, a chromatin-remodeling complex, to open chromatin during replication to mediate maintenance of active chromatin states (Poot et al., 2004).
Mr. Perfect's unconscious chemistry machinery has also been activated.
Impairment of the ERAD machinery has also been reported in other neurodegenerative diseases.
In addition to serve as a "filter" of genetic noise, the NMD machinery has also been described as an important regulator of mRNA output.
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And, though most hopes for recovery are pinned on the business-investment cycle, orders for machinery have also sagged.
The preferred targets are semi-trucks with tanks that hold as much as 500 gallons of fuel, but regular cars and heavy machinery have also attracted their attention.
Other components in the RNAi machinery have also been shown to play a role.
Our analyses indicate, moreover, that not only SPS2, but also other crucial components of the selenoprotein biosynthesis machinery have also been lost in D. willistoni.
Components of the ESCRT machinery have also been linked to the formation of extracellular vesicles (EVs) that are secreted by many (if not all) cell types.
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