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They therefore cannot deal effectively with unmodeled dynamics and large parameter variations that can lead to scrap runs and machinery damage.
Myriad factors related to production and distribution (including weather, pests, machinery damage, package damage, transportation delays, supply and demand variability, etc).
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Its entire stock of raw ingredients was lost and valuable hi-tech machinery damaged beyond repair.
Some of it could contain high concentrations of sulfur and chlorine, which could corrode machinery and damage the astronauts' lungs.
Saffron, the dried orange-red flower stigmas of the fall-blooming Crocus sativus, must be harvested by hand because machinery would damage the leaves, which are needed to produce food for the plant.
Superoxide dismutases act as part of the cellular antioxidant system protecting the redox sensitive cellular machinery from damage induced by reactive oxygen species (ROS).
The emerging picture is that of a complex interplay between the conventional DNA replication machinery, DNA damage response factors, and a specialized set of proteins that help to recruit and regulate the telomerase enzyme.
Reduction of cleaved PARP suggests that the cell's chromatin and DNA repair machinery was damaged due to Cuc IIa treatments.
In mutator strains, that is, genomes in which the DNA repair machinery is damaged, leading to elevated mutation rates, the mutation rate rises orders of magnitude, up to ~10-7 – 16-6 [ 16].
In addition to the core apoptotic machinery, DNA damage-induced apoptosis also depends on the tumour-suppressor p53 homologue CEP-1 and the BH3-only proteins EGL-1 and CED-13.
Some osmoprotectants also protect the metabolic machinery against oxidative damage.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com