Sentence examples for machinery coordinates from inspiring English sources

Moreover, we show that cardiac-structural genes and cardiac-transcription factors have distinct epigenetic mechanisms to regulate their gene expression, providing a better understanding of how the epigenetic machinery coordinates to regulate gene expression in different cell types.

Modeling the fiber orientation (tangent) τ, the drift term with the potential V describes the typical coiling behavior of the fibers, i.e., (V boldsymbol{xi})=boldsymbol{xi}cdotmathbf{C}^{-1}cdot boldsymbol{xi}/2) with (mathbf{C}=operatorname{diag}(sigma_{x}^{2},sigma _{y}^{2},sigma_{z}^{2})) regarding the machinery coordinates.

Overall, our analysis provides new insights into the mechanisms of hCM transcriptional regulation, and stands as an informative and rich resource for investigating cardiac gene functions, as well as providing a better understanding of how the epigenetic machinery coordinates to regulate gene expression in different cell types.

As the postnatal expansion of the GCP population requires a functional Shh signalling machinery coordinated by the primary cilium, the proliferative ability of these cells is thus dependent on the presence of intact cilia structures62,63.

The Sec complex forms the core of a conserved machinery coordinating the passage of proteins across or into biological membranes.

We have taken advantage of the versatility of the sperm model to investigate how cAMP, calcium, and the proteinaceous fusion machinery coordinate to accomplish secretion.

Thus, the majority of genes revealed by the screen may perform conserved functions throughout metazoans as components of the machinery coordinating cell cycles with development.

This is likely linked to the observed abnormal distribution of F-actin in the absence of Ret, which indicates a lack of appropriate growth signals and abnormal activity of the underlying signaling machinery coordinating actin dynamics.

Upregulation of gene sctL, encoding components of type III secretion machinery, possibly coordinates protein secretion system in P. temperata for translocating effector molecules across the bacterial cell envelope into host cells [ 38- 40].

Thus, it is likely that dysfunctional CSPα affects the machinery that coordinates these lysosomal fusion events resulting in the formation of the ceroid aggregates and subsequent swelling of the cellular soma (cortical pyramidal neurons and palmar sweat gland) seen in AD-ANCL.

However, how translational machinery is coordinated to meet the translational demands remains elusive.