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Here we report that sciatic nerve lesion elevates levels of m6A-tagged transcripts encoding many regeneration-associated genes and protein translation machinery components in the adult mouse dorsal root ganglion (DRG).
Presence of highly specialized versions of core transcription machinery components in germ cells raises this fundamental question why these cells need a different core transcription apparatus.
We next evaluated whether impaired adaptations in mitochondrial protein import machinery components in old animals would coincide with reduced functional rates of protein import into the organelle.
These results suggest that the function of RNT-1 as a transcription factor is closely related with specific transcriptional machinery components in C. elegans.
In line with the global transcriptional response, the volcano plot in Figure 5A shows that the machinery components in all three strains have similar transcriptional responses to α-amylase overproduction (Pearson correlation coefficient > 0.95).
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Mr. Lee said medium-size Japanese companies agreed to invest in electronics and machinery components factories in South Korea.
To complement and accomplish the A. oryzae component list, we also included the machinery components previously reported in A. oryzae[ 10- 12] and blasted for the A. oryzae homologs of the reported components in A. nidulans[ 13] and A. niger[ 11, 14], as being in the same genus they share many common mechanisms and pathways.
These phenomena reflect that the secretory machinery components are duplicated in A. oryzae.
From a broader perspective, we expect that further studies on the extensive RNA silencing machinery components evolved in crop plants may lead to new discoveries about their functions in shaping plant diversity with regard to phenotypes and innate immunity mechanisms.
Duplication of cell-cycle machinery components is rare in metazoans but it is a widespread phenomenon in plants [ 35- 38].It has been proposed that duplication, followed by sequence divergence of promoter and/or coding regions, leads to novel and specialized functions unique to the plant kingdom [ 23, 39].
The transcriptional changes of all the machinery components are summarized in Additional file 2: Table S1.
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