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These results suggest that, under certain conditions, the calcium-mobilization arm can influence the protein machinery arm of the cascade.
Because PTP1BD181A acts on the fusion machinery arm after the point of crosstalk, we predicted that it would not prevent external calcium-induced-acrosomal calcium mobilization.
Furthermore, these data strengthen the observations made with the anti-Rab27/Rab27A anti-Rab27/Rab27Athat the calcium mobilization areversiblehe pairein machinery arm thatucceed.
Data shown in Figure 3 indicate that blocking the fusion machinery arm at the stage when Rab27 is required halted the calcium mobilization arm of the pathway.
This result suggests that maintaining the protein machinery arm artificially off with PTP1BD181A made the system refractory to an intracellular calcium mobilization blocker.
Because the anti-Rab3 antibodies halt the fusion machinery arm at or before the point of crosstalk, we hypothesized that they should interfere with acrosomal calcium mobilization.
Similar(46)
This is not like carmaking and it is one reason why Fiat is demerging its car business from its lorry, tractor and machinery arms.
Taken together, our results indicate that there is a connection between the calcium mobilization and protein machinery arms downstream of Rab3 and upstream of PTP1B.
The resulting pig iron was melted again in additional furnaces and then poured, molten, into casting molds for tools, machinery and arms.
He suffers an accident in which his left hand is caught in machinery, and his arm is dragged in up to the shoulder.
And, there's much more - the numismatic, archeological and musical instrument collection as well as early mechanical arts - tools, machinery, kitchen equipment, arms, military accouterments, scientific and medical instruments, and clocks and watches.
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