These complex machineries are comprised of structural and regulatory subunits, components with distinct functions (e.g., DNA segregation, PG precursor synthesis and transport), and PG biosynthetic and modifying enzymes.
The geometric dome, which accommodates the entirety its machinery, is comprised of a lattice of glass and photovoltaic panels.
The positive limb of the mammalian clock machinery is comprised of CLOCK and BMAL1, which are transcription factors that heterodimerize through the PAS domain and induce the expression of clock-controlled genes by binding to their promoters at E-boxes.
The ESCRT machinery is comprised of four complexes that regulate the formation of multivesicular bodies (MVBs) in the late endosome.
The clock machinery is comprised of oscillatory positive and negative transcriptional-translational feedback loops involving the clock-related genes and their products (9, 10).
Giardia lamblia is a parasitic protist with unusual genomic traits: it is binucleated and tetraploid, has a very compact genome, displays a theme of genomic minimalism with cellular machinery commonly comprised of a reduced number of protein components, and has a remarkably large population of long, stable, noncoding, antisense RNAs.
To this end, we defined the main processes included in the gene expression pathway, listed the known components of the corresponding machineries in D. melanogaster (16 machineries comprising 664 proteins), and identified their orthologs in Ch. tentans as follows.
Either to avoid or to scavenge oxidative damage, mammalian cells possess inherent antioxidant machinery, which is comprised of superoxide dismutase (SOD), catalase, and glutathione peroxidase (GPx) [ 18].
Across the samples, genes associated with the cell's replicative machinery comprised the largest portion of over-represented transcripts by total normalized number of mapping reads in most samples.
Traffic was equally heavy at both industrial and residential sites, but large trucks and machinery comprised a larger proportion of the traffic in the industrial areas.
This machinery comprises over a hundred proteins [12], all of which are putative candidate genes for translation deficiencies in human.
