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The effect of blending MACE and Walloon information was also studied for internal animals that were not associated with MACE information and that were sired by internally used sires by considering (1) r between EVALBL and EVALW, EVALBLNN, EVALBLRE or EVALBLR, (2) REtot and (3) average REL.
Even if MACE allows the aggregation of EBV for dairy sires, internal genetic evaluations for animals not associated with MACE information (e.g., cows, calves, young sires) are not influenced by external information considered by the MACE for dairy sires and may be still biased.
The TSA was therefore applied for Walloon and MACE information.
Walloon and MACE information were blended by considering only double-counting of contributions due to records (EVALBLRE, EBVBLRE, RELBLRE).
The effect of the integration of MACE information on predictions was also studied for internal animals that were not associated with MACE information and that were sired by internally used sires.
Blending of Walloon and MACE information led to similar rankings of the 631 sires for the four blending evaluations.
Similar(24)
Traditional MACE combines information from domestic and foreign relatives to increase reliability.
GO categories for MACE data were annotated using the UniProt-GOA database (EBI) and information by ENSEMBL.
Criteria for the diagnosis of MACEs and collection of any information regarding MACEs have previously been described (14, 16).
MACEs, based on information available in the hospital chart, included heart failure (defined by NYHA class III or IV), peripheral embolism, stroke, heart valve intervention and cardiovascular death.
Information about MACE was obtained from hospital records or telephone contact with patients, relatives of patients or the referring physician.
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