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Three cynomologus macaques were vaccinated with 1 dose of 10 PFU of VSVΔG/LASVGPC, a live-attenuated, recombinant viral vaccine in which the VSV surface glycoprotein has been replaced with those of LASV, by intramuscular injection as described (4 ).
Groups of three cynomolgus macaques were vaccinated with VRP that expressed EBOV GP, EBOV NP, a mixture of EBOV GP and EBOV NP, or a control antigen (influenza hemagglutinin) that has no effect on EBOV immunity.
The marginal PRNT did not preclude challenge of the monkeys; however, in previous studies, similar results were obtained when cynomolgus macaques were vaccinated with the VRP expressing MBGV genes, yet the animals were protected from lethal disease (12).
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To address this straight forward question, three Mamu-DRB*W201+ macaques that were vaccinated for 2 years with BCG were evaluated in this study.
Twelve Indian rhesus macaques (Macaca mulatta) were vaccinated intravenously with 106 CFU of BCG and used screening epitope peptides of Ag85B.
Although we studied 22 macaques in total, only smaller subsets of these were vaccinated and larger studies will help validate this work.
Around half were vaccinated against measles.
2057 people were vaccinated.
Survivors were vaccinated against typhoid and tetanus.
Only the fortunate few babies were vaccinated.
Among them, 172 (2%) were vaccinated.
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CEO of Professional Science Editing for Scientists @ prosciediting.com