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Blood and mucosal samples of non-immunized macaques were supplied periodically as controls.
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Additional DNA samples were supplied by Bill Hopkins, Emory University (chimpanzee), Allyson Bennet, Wake Forest University (chimpanzee, rhesus macaque, bonnet macaque), Mar Sanchez, Emory University (rhesus macaque), and Anne Yoder, Duke University (galago).
The data were supplied.
Detailed description of the human, rhesus macaque and murine samples and extraction protocols are supplied in Text S1 and Table S1.
First, twenty-four rhesus macaques were infected with the Lyme bacteria in the laboratory.
There, people and macaques were mingling on the beach in some friendly interspecies contact.
An additional three macaques were gestation day (GD) matched control placebo-inoculated animals.
The macaques were prepared as previously described [14, 15].
The macaques were fasted overnight before each study.
Macaques were boosted with rhFLSC protein.
Twelve macaques were vaccinated with a bacteriophage Qß-based vaccine targeting macaque CCR5 (Qß.CCR5).
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