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Distal duodenum tissue samples collected from gluten-sensitive FH09 and control FR26 macaques were processed as described in detail previously [18].
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In addition, the entire set of recent human substitutions; that is, those nucleotides that differed in human but were the same in chimp and macaque, were processed for the MRI and control regions and presented as "fixed substitutions".
Raw data from the Rhesus Macaque Genome Arrays were processed using GC-RMA normalization [9].
Fresh or frozen liver from mouse, rabbit, macaque, and dog were processed for Hi-C or 4C-seq libraries.
Approximately 350 rhesus macaque fecal samples were processed: 150 from Covance (Vienna, VA, USA), 100 from the New England Primate Research Center (Southborough, MA, USA), and 98 from the Tulane National Primate Research Center (Covington, LA, USA).
In 1966, to study adaptation processes, a total of 57 rhesus macaques were released onto the remote 1.2-km island.
First, twenty-four rhesus macaques were infected with the Lyme bacteria in the laboratory.
There, people and macaques were mingling on the beach in some friendly interspecies contact.
An additional three macaques were gestation day (GD) matched control placebo-inoculated animals.
The macaques were prepared as previously described [14, 15].
The macaques were fasted overnight before each study.
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