Similar to HIV-infected patients, SIV-infected macaques present with myocardial hypertrophy (enlarged myocytes with irregular nuclei), fibrosis, with increased collagen deposition (Fig. 2b) that replaces either small groups of drop-out myocytes or larger areas of infarction and myocarditis, with infiltration with mononuclear cells (Fig. 2c), and myocytolysis.
Furthermore, when rhesus macaques are presented with binary choices between two types of juice in variable amounts, neurons in the orbitofrontal cortex encode the value of the offered and chosen juices in a menu invariant way, suggesting that preference transitivity might be rooted in the activity of these neurons [23].
Dr. Tsao used functional magnetic resonance imaging to record which areas of the brain were activated when macaque monkeys were presented with stimuli including fruits, gadgets, scrambled patterns — and faces.
Eight adult male rhesus macaques (four L/L and four S/L) were presented with a series of images depicting faces (see Figure 1A) or scrambled faces of familiar macaque monkeys (see Figure 1B for task sequence).
Rhesus macaque, a non-human primate model, infected by the H9N2 virus, presented with biphasic fever and viral pneumonia, and the virus replicated in both their upper and lower respiratory tracts (Zhang et al., 2013a).
A 9-year-old female rhesus macaque (Macaca mulatta) with a history of a previous caesarian section presented with a large, firm uterine mass on abdominal and rectal palpation at routine semi-annual physical exam.
This characteristic seems to be shared with non-human primates since different sub-regions of the primary auditory cortex of macaques present different functional characteristics in term of tonotopy, latency and frequency tuning [48], [49].
Interestingly, erythrocytes from neither mice nor rhesus macaques present CAR.
Conversely, macaques infected with SIV recapitulate all the biological features of chronic HIV infection, and thus present with increased levels of chronic immune activation, inflammation, and microbial translocation [ 34, 14, 33, 31].
The seroprevalence of SFV among the Sangeh macaques is presented in Table 1.
