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EDL 2 - MAC 1.
To the Editor: Mycobacterium marseillense was recently described as a new species belonging to the Mycobacterium avium complex (MAC) (1 ).
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Setanta's on-screen clock reads "Mac 1-0 Sco".
The structures also offer insight into the functional difference between Mac-1 and Mac-2.
Macrophage antigen 1 (Mac-1).
However, piperlactam S failed to modify Mac-1 expression.
BoX-MAC-1 and BoX-MAC-2 are selected to analyze cross-layer design approaches.
Despite the lack of sequence homology, Mac-1 adopts the canonical papain fold.
Mac-1 forms a symmetric dimer in both crystal forms and displays the unique dimer interface among papain superfamily members.
Here, we report the crystal structures of Mac-1 and its catalytically inactive C94A mutant in two different crystal forms.
Functional inhibition by antibodies suggested that Mac-1 (CD11b) integrin plays a central role in complement 5a-induced migration.
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