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Another score was added according to the distribution of lymphocytes, such as: score 1: scattered lymphocytes; score 2: scattered lymphocytes and clusters.
In non-neoplastic ovaries, the same CD scoring system was applied for analysing the presence of lymphocytes (score 1 3) in three randomly chosen HPFs within the entire tissue section.
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CD38 expression was determined in CD3+/CD8+ lymphocytes (CD8 T lymphocytes) and CD3+/CD8- lymphocytes (scored as CD4+ T lymphocytes).
CD45RA/CD62L-expression was determined in CD3+/CD4+ lymphocytes (CD4 T lymphocytes) and CD3+/CD4- lymphocytes (scored as CD8+ T cells).
It was found, unexpectedly, that the presence of metastases did not invalidate the correlation between lymphocyte score and survival.
Infiltrates were characterised according to the score (grade 1, <50 periductal <span class="lh">lymphocytes; grade 2, >50 lymphocytes; grade 3 = grade 1 or 2 plus GC).
Examples of specific increased function among those categories are 'leukocyte migration' (Z-score 5.006), 'inflammatory response' (Z-score 4.578) and 'quantity of T lymphocytes' (Z-score 3.934).
CD38+ lymphocytes were scored as activated cells.
CD45RA/CD62L-positive lymphocytes were scored as naïve cells.
Steatohepatitis cases had the highest C-reactive protein, lymphocytes, Framingham scores and predicted coronary risks.
FOXP3+ T lymphocytes were scored in 5 10% increments as a percentage of total CD3+ staining cells in several high magnification fields.
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