Additionally, mmCD40Ig only showed mild immunosuppressive activity in a one-way mixed lymphocyte reaction (MLR) system.
Donor specific alloreactive response was studied in a mixed lymphocyte reaction assay.
BMDC function was evaluated by an allogeneic mixed lymphocyte reaction (MLR) assay.
LIGHT-modified DCs enhanced allostimulation for T cells in mixed lymphocyte reaction (MLR).
Further, we found, using a mixed lymphocyte reaction, that the extract was able to significantly reduce CD8+ T cell activity.
Furthermore, mini-yCD3 was effective in modulating T-cell receptor/CD3 and inhibiting mixed lymphocyte reaction with similarity as yCD3.
A significantly higher T-cell depletion (revealed by mixed lymphocyte reaction, [MLR]) was found for AMSCs (vs. BM-MSCs) at both non- and differentiated stages.
To better understand the alloresponse between HLA-identical related pairs, we characterized the alloreactive T cells generated in a mixed lymphocyte reaction (MLR) assay system.
HA PD-1 Ig showed enhanced binding to human dendritic cells, and increased T cell proliferation and cytokine production in a mixed lymphocyte reaction (MLR) assay.
Graft function and tolerance induction were assessed by mixed lymphocyte reaction (MLR), flow cytometry (FCM), and full-thickness skin graft studies.
This finding was supported by an in vitro mixed lymphocyte reaction assay that revealed impaired priming of T cells by CD137L-deficient dendritic cells upon mycobacterial infection.
