Sentence examples for lymphocyte extravasation from inspiring English sources

Lymphocyte extravasation requires that emigrating cells process chemoattractant signals, typically mediated by chemokines, encountered on endothelial surface (apical) and subendothelial (basal) compartments.

Selectin mediated binding initiates the earliest step of lymphocyte extravasation by slowing lymphocyte rolling along HEVs.

Recent work supports the hypothesis that Natalizumab does not uniformly block lymphocyte extravasation but might act via selective modulation of its cellular targets.

Peeling et al. [ 100] found that the immunosuppressant FK-506 (tacrolimus) reduced lymphocyte extravasation after ICH.

This leads to subendothelial basement membrane degradation followed by endothelial cell retraction, allowing neoplastic lymphocyte extravasation.

A recent study showed that low-dose NGR-TNF (0.1 ng) promotes lymphocyte extravasation in tumors [ 45].

Furthermore, sphingosine-1-phosphate maintains endothelial cell integrity and inhibits lymphocyte extravasations via the sphingosine-1-phospate receptor.

Gαi2 proteins were reported to be involved in T-lymphocyte extravasation, including in brain [ 74, 75].

For a pore size less than the diameter of the cell, backpacks were still attached, perhaps indicating a sufficiently strong cell−backpack association required for a backpack to remain attached to a lymphocyte undergoing extravasation in vivo.

Glycam1 can participate in lymphocyte attachment and extravasation into the blood vessel wall [ 19], and plasma levels of this molecule are found up-regulated in inflammation [ 20].

Intriguingly, a positive correlation between vascular CD54 and percentage of tissue occupied by leucocyte infiltrate was demonstrated only in benign prostate tissue but not in foci of carcinoma (Table 1), thereby implying that this CAM contributes to extravasation of lymphocyte in tissue not affected by malignant transformation.