Sentence examples for lymphocyte adhesion molecules from inspiring English sources
NO apart of being a vasodilator, also reduces vascular permeability and the monocite and lymphocyte adhesion molecules synthesis.
Chemokines on the vascular lumen then activate lymphocyte adhesion molecules to promote extravasation (Ley et al, 2007).
Interaction of AGE-AGE-specific receptors has also been linked with the activation of nuclear factor- κB and oxidative stress, which leads to hyperexpression of lymphocyte adhesion molecules, proinflammatory cytokines, procoagulant factors, and vasoactive mediators [ 30].
It is worth noting that in patients with rheumatoid arthritis (RA) treated with leflunomide (the parent compound of teriflunomide), infiltration of macrophages and T cells into the synovial tissue was reduced, and expression patterns of lymphocyte adhesion molecules and matrix metalloproteinase were altered, suggesting an effect of teriflunomide on lymphocyte migration [ 82].
Although immunologic and inflammatory responses may be important factors, the direct role of circulating neutrophil phagocytosis and lymphocyte adhesion molecule expression has yet to be investigated in exertional heatstroke (ExHS).
Early characterization of Sn expressed on macrophages identified it as a lymphocyte adhesion molecule that binds sialic acid conjugates on T cells [12], specifically CD43 [40].
Originally, sialoadhesin was characterized as a lymphocyte adhesion molecule, though recently its involvement in internalization of sialic acid carrying pathogens was shown, suggesting that sialoadhesin is an endocytic receptor.
Natalizumab, an α4 integrin antagonist, blocks the binding of lymphocytes to adhesion molecules on the vascular endothelium, which could effectively decrease lymphocyte trafficking primarily to the gut and brain.
Sialoadhesin was first described as a lymphocyte cell adhesion molecule expressed on macrophages localized in secondary lymphoid organs [12] and later as a protein restricted to a subset of activated macrophages related to inflammatory responses associated with rheumatoid arthritis and atherosclerosis [13].
CD22, a 140 kDa transmenbrane type 1 protein, also called Sialic acid-binding Ig-like lectin 2 (Siglec-2) or B-lymphocyte cell adhesion molecule (BL-CAM), is a member of the Siglec family that binds to α2-6-linked sialic acids on glycoproteins.
An increase of VEGF-A in the initial phases of relapse is compatible with its role as a pro-inflammatory factor that attracts monocytes and lymphocytes, upregulates immunomodulatory adhesion molecules, stimulates secretion of proinflammatory cytokines, and increases blood-brain barrier permeability [22], [34].
