Sentence examples for lying downstream of from inspiring English sources

Thus, AURKB and WEE1 are targets and biomarkers of therapeutic efficacy, lying downstream of V600EB-RAF in melanomas.

In support of p27 lying downstream of AMPK on the activation of autophagy in Tsc2-null cells, a p27 mutant that preferentially localizes in the cytosol recovered the effect of rapamycin on autophagy in both p27- and LKB1-depleted cells, but a nuclear p27 mutant was inactive.

To identify cell cycle factors lying downstream of the C/EBPβ signal, we performed a screen of transcriptional targets of C/EBPβ using a microarray analysis (Table S1).

The discrepancy may be due to the diversity of signaling pathway(s) lying downstream of cGKII and upstream of C/EBPβ.

cGKII is a serine/threonine kinase lying downstream of the C-type natriuretic peptide pathway which is essential for skeletal growth [40].

Key effectors lying downstream of PIP3 that promote tumorigenesis include such molecules as PDK1, Akt/protein kinase B (PKB), and the two mammalian target of rapamycin-containing complexes, mTOR1 and mTOR2 [11], [11].

Excessive levels of hexavalent chromium were also found at the entrance to Huangnibao Reservoir, which lies downstream of Chachong.

The problem, researchers concluded, lay downstream of that processing, in the interplay among higher-level processing regions of the brain.

This is indicative of a block in division that lies downstream of FtsZ assembly.

These results imply that Cby lies downstream of Foxj1 in ciliated cells.

In this study, we provide evidence that β-catenin lies downstream of WNT4 to suppress expression of activin βB.