In the study by Hector et al., it is possible that either YKL-40 generated in the lungs "spilled over" into the serum of their patients or that the serum levels reflected systemic inflammation.
In a literature, it has been implicated that in COPD patients inflammatory mediators generated in the lung may "spill over" into the circulation and then activate the liver to release inflammatory proteins, which may be the real detrimental factors to target organs and the resource of systemic inflammation.
Lambert suffered a number of injuries during his career, including in 1987 when he broke his ankle and cheekbone and had a collapsed lung in a spill at a track in Pleasanton.
Just when jockey Flavien Prat, a native of France, was working himself into the conversation as one of the go-to riders in Southern California horse racing, he suffered five fractured vertebrae in his back and a punctured lung during a spill at Los Alamitos on Sept. 17.
One of the early thoughts was that particles could cause changes to the primary target organ, the lung, which would spill over into the vascular system and secondarily affect autonomic function.
The Green News Report is also available via... IN TODAY'S RADIO REPORT: Republican candidates continue to dodge the climate change question; Mountaintop removal coal mining promotes lung cancer; 'Significant' oil spill in Louisiana bayou; 2014 on track to be hottest year on record; PLUS: LEGO breaks up with Shell Oil..
But the only thing like that I ever worked on was the oil spill". The lungs of Tim Burt of Seldovia, Alaska, were coated with oil while he was steam-cleaning oil tanks.
Although in this study we did not specifically measure the systemic inflammatory load of the study participants, one of the most obvious explanations for the presence of systemic inflammation in COPD is that local inflammatory processes occurring in the lung may cause a "spills over" of proinflammatory molecules into the systemic circulation [ 12].
Kerry Sheridan, AFP, "BP oil spill caused dolphins' lung disease, deaths: study," May 21 , 2015
Dolphins are suffering health issues following the BP oil spill including miscarriage, lung disease and teeth loss.
