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Lung function, symptoms and safety are also assessed.
Significant improvements over baseline were reported in both groups in terms of lung function, symptoms and use of rescue inhaled salbutamol.
Conversely, no effects over lung function, symptoms or quality of life were detected [ 33].
The secondary endpoints included lung function, symptoms and the need for corticosteroid burst and peripheral eosinophil count.
These subjects were not significantly different from the 196 in terms of lung function, symptoms or health status.
Clinical studies have confirmed the efficacy of formoterol for bronchodilation in COPD in terms of improved lung function, symptoms, exacerbations, and HRQL [ 15- 20].
Similar(40)
In shorter term studies a modest dose response effect of ICSs has been shown for lung function, symptom control and oral corticosteroid use in asthmatic patients.
Secondary endpoints included lung function, symptom scores, symptom-free days and use of rescue medication, St . Georges Respiratory Questionnaire, six minute walking test and COPD exacerbations.
This is evident for ever, current and ex smoking, and for outcomes based on mortality, lung function, symptom prevalence or other methods.
The benefits of adding long-acting β2 agonists (LABAs) to an ICS in twice-daily treatments are well documented for lung function, symptom control, rescue medication use and asthma exacerbation frequency [ 13].
Improvements in lung function, symptom control and rescue medication use, and reductions in risk in time to first exacerbation requiring systemic corticosteroids, and in the annual rate of asthma exacerbations requiring systemic corticosteroids, were all significantly in favour of treatment with QMF149.
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