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Changes in lung function resulting from the allergen challenge were assessed by calculating lung resistance (RL) and dynamic lung compliance (Cdyn) using Pp and air flow recorded values.
IAH is also associated with atelectasis and impaired lung function, resulting from a cephalad shift of the diaphragm [ 7- 10].
Repeated episodes of ACS negatively impact long-term lung function, resulting thereby in chronic lung diseases [ 10].
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This change in lung function resulted primarily from a decline in lung function among those receiving placebo.
Significance of lung function results was calculated using the Chi squared test.
Demographic details, adverse events (AEs) and where available lung function results were retrospectively collected from clinical letters.
The significance of the lung function results may be biased towards those with less severe disease and those that survived.
We focused on demographic information, reasons for starting nintedanib, frequency and type of AEs whilst on treatment, discontinuation rates and pre-treatment lung function results for all centres.
The results of univariate analysis of factors potentially associated with baseline lung function at 9 years of age are shown in Table 2. Previous lung function results and the clinical history, but not current clinical status, were significantly related to lung function results at age 9 years.
Nevertheless, certain variables, such as lung function results, were unavailable and could not be controlled.
Our lung function results show that exposure to particles generated indoors, but not outdoors, was associated with decrements of lung functions except for MEF.
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