Ai Feedback
Exact(4)
Improvements in lung function demonstrated in RCTs, in conjunction with significant reductions in sweat chloride levels, are without precedent in cystic fibrosis and appear to be disease-modifying.
Despite these limitations, over the 5 year follow-up of BT treated subjects, the absence of unexpected respiratory adverse events, no increases in hospitalizations or emergency room visits for respiratory symptoms, and maintenance of stable lung function demonstrated safety of BT out to 5 years.
The less substantial improvements in lung function demonstrated in the TRAFFIC and TRANSPORT studies and approval of ivacaftor/lumacaftor in 2015 by the FDA in the United States are likely to generate further discussions about the cost benefit ratio associated with treatment [ 7].
Epidemiological panel studies that examined the effect of PM on lung function demonstrated greater declines in forced expiratory volume in 1 sec and forced vital capacity in individuals with COPD versus those without in response to PM2.5 exposure (e.g., Lagorio et al. 2006; Trenga et al. 2006).
Similar(56)
The significant decrements in lung volume and function demonstrated by infected PAI-1−/− mice at 3 days appeared to be due to the presence of pleural effusions rather than advanced pleural remodeling.
Children with CTM have impaired lung function as demonstrated by the significant differences in LCI, reactance and FEV1 but not FVC, resistance and TLC.
Sunyer et al. (2008) [ 36] assessed the association between rs1205 and lung function; they demonstrated that the TT homozygous genotype in the CRP gene is associated with better lung function.
We hypothesise that sensitive measures of lung function will demonstrate residual impairments in CTM compared to healthy children.
In fact, individuals who demonstrate improvements in lung function may also demonstrate an increase in exacerbation frequency.
An association between body mass index and reduced lung function has been demonstrated [ 12, 13].
Among those that have, reduced lung function has been demonstrated among adults with increased traffic exposure (Evans et al. 1988; Kan et al. 2007; Karita et al. 2001; Schikowski et al. 2005; Sekine et al. 2004), although some studies have found no association (Nakai et al. 1999; Tollerud et al. 1983).
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com