Sentence examples for lung defect from inspiring English sources

A clone was produced from preserved tissues, but it died from a severe lung defect within minutes of being born.

Interestingly, the lung defect that resulted from RA-deficiency could be reproduced in RA-sufficient foreguts by hyperactivating Tgfbeta signaling with exogenous TGF beta 1. Preventing activation of endogenous Tgfbeta signaling with a pan-specific TGFbeta-blocking antibody allowed bud formation and gene expression in the lung field of both Raldh2-null and BMS493-treated foreguts.

Blancornelas was taken to the hospital on November 19 after his son confessed that his father had a lung defect that dated back to his youth.

Using immunohistochemistry, we determined the localisation of Creb1 protein at E16.5 and E18.5, timepoints which occur before and after the onset of the lung defect at E17.5 observed in Creb1−/− mice.

Pulmonary function tests revealed restrictive lung defect characterised by reduced vital capacity and lung diffusing capacity.

Reduced FVC does not prove the presence of a restrictive lung defect, but is suggestive of pulmonary restriction when the FEV1/FVC is normal or increased.

The results demonstrate a new mechanism of boundary formation in complex, 3D organs and provide new insights into glucocorticoid therapies for lung defects in premature birth.

Remarkably, endotracheal treatment with exogenous PDGF-A rescues both the lung defects in haploinsufficient mice undergoing MV-O2 Overall, our results establish attenuated PDGF signaling as an important driver of nCLD pathology with provision of PDGF-A as a protective strategy for newborns undergoing MV-O2.

4) Fgf10 heterozygous pups display increased sensitivity to hyperoxia exposure associated with significant structural lung defects.

Many of the animals cloned to date have had serious health problems at or shortly after birth, including lung defects.

While babies with ALSG or LADD do not display apparent lung defects, adult patients with heterozygous loss of function of FGF10 exhibit a significant decrease in inspiratory vital capacity (IVC), forced expiratory volume in one second (FEV1), and FEV1/IVC quota compared to non-carrier siblings and predicted reference values [51].