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Diphyllin apioside-5-acetate and neojusticin B showed cytotoxic against the cultured rabbit lung cell [14].
L-MSCs orchestrate lung cell growth and therefore play an important role in normal development.
The findings suggest that licorice compounds seem to prevent the nitrogen species-mediated lung cell damage.
Addition of earth materials to lung cell cultures can trigger an increase in ROS within the cells [42, 43].
The peak of detectable glucose metabolism on day 14 after murine pneumonectomy is consistent with known lung cell dynamics.
Further studies were conducted in the human epithelial lung cell line, A549, to explore the molecular mechanism of silica toxicity.
Compounds 8a, 8b, 8q, 8t, and 8u showed high selectivity indices towards cancer cells over L132 normal lung cell line.
The exact relationship between Cgrp+ cells (which include mostly the neuroendocrine cells) and other lung cell types during normal development and homeostasis is still under investigation.
Using new gene-editing approaches and other technologies, rapid advances in understanding lung cell origin have been made in the last decade, particularly in mouse lung development.
Our results provide global profiles of engineered lung cell fates, a guide for improving their directed differentiation, and a human model of the developing airway.
These findings confirm the usefulness of systems allowing delivery of airborne smoke constituents to lung cell monolayers during studies of the molecular basis for acute smoke intoxication injury.
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