Exact(2)
As a physical background material, it has functions in space filling, lubrication, shock absorption, and protein exclusion.
Viscosupplementation involves the use of intra-articular injections of hyaluronic acid (HA), a glycosaminoglycan that provides joint lubrication, shock absorbency, and acts as the backbone for the proteoglycans of the extracellular matrix [ 4].
Similar(58)
HA is the primary component of synovial fluid and provides the joint with lubrication and shock absorption [23].
The menisci play an important role in knee joint stability, joint lubrication and shock absorption and help to maintain the integrity of the articular cartilage [ 2, 3].
HA is responsible for the viscosity and elasticity of synovial fluid and thus plays roles in lubrication and shock-absorption.
Hyaluronic acid is a polysaccharide that is the main constituent of cartilage and synovial fluid; it is responsible for the mechanical properties of the joint by allowing shock absorption, lubrication and cartilage protection [11].
The meniscus plays important roles in the knee joint, including load transmission at the tibiofemoral articulation, shock absorption, lubrication, and stabilization of the knee joint, though its healing capacity remains limited.
The meniscus is known to play important roles in load share, shock absorption, lubrication, and knee stability [ 1- 3].
This means that they need lubrication, are impaired by magnetism, shock, heat and cold, and wear out.Silicon shirks these problems.
It is believed that this decrease in joint lubrication and reduction in the shock absorbing mechanism in OA can be remedied by intra-articular viscosupplementation.
IA-HA has been proposed to have many therapeutic mechanisms of action in the OA knee, including shock absorption, joint lubrication, anti-inflammatory effects, chondroprotection, proteoglycan synthesis, and cartilage matrix alterations [ 2].
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