Exact(21)
To further explore the role of Lpd in CCP scission during EGFR endocytosis, we examined Lpd knockdown and control HeLa cells after starvation and stimulation with 2 ng/ml EGF for 2 min by transmission electron microscopy.
Because c-Abl [ 7] and Lpd positively affect dorsal ruffling, we investigated whether c-Abl might regulate Lpd in this process.
We observed more invaginated, omega-shaped, and tubulated CCPs in Lpd knockdown cells compared to control cells further supporting a role for Lpd in CCP scission.
Finally, we included 13 RCTs reporting the effects of LPD in diabetic patients.
Except two cases, all cases describe female patients, so occurrence of LPD in males is extremely rare.
BATF drives formation of an LPD in mice by suppressing the T-cell response to intrinsic apoptotic signaling.
Similar(39)
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