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Threshold for eliciting MEP was defined as the lowest stimulus intensity (% of maximal stimulator output) capable of eliciting at least five MEP with an amplitude of at least 100 μV in a relaxed hand muscle in a series of ten consecutive trials of TMS [27].
The ABR threshold was defined as the lowest stimulus intensity that produced a replicable waveform response.
Yellow and green, representing visual stimuli in the top most and the lowest stimulus positions, were not observed.
Characteristic frequencies (CFs) were defined at each site as the frequency that evoked reliable spike discharges at the lowest stimulus intensity.
Therefore, the genetic factors, sex or sensitization have in fact modulated the lowest stimulus' strength at which the subject indicated pain.
However, the CTD with the greatest threshold variation- the uniform distribution- produced the lowest stimulus per site, but the greatest fluctuation amplitude (Figure 10).
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Additionally incubation with EGTA-AM unmasked a modest acceleration phase for the lowest stimuli.
All 6 participants exhibited the increasing pattern for the two lowest stimuli, and 4 of the 6 exhibited the decreasing pattern for the two highest stimuli in the base set.
This rapid transient or phasic response is not observed at low stimulus flow rate (e.g. 7.5 ml/min).
However, very low stimulus frequencies (0.17 to 0.08 Hz) can maintain this enhancement after TSSP and windup have occurred.
IGF-1-treated myocardium exhibits an enhanced PTD-Ca2+ response and a better intracellular Ca2+ replenishing ability at the low stimulus frequencies.
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