Sentence examples for lowest sequence coverage from inspiring English sources

The lowest sequence coverage was 2×, for just one nucleotide position (nucleotide position 67).

The lowest sequence coverage that gives the requested FDR is then used as the cutoff value.

These two horses also had the lowest sequence coverage, which is the most likely explanation for the low genotyping concordance.

Over 90% of SNPs from those with the lowest sequence coverage included in the validation study (minor allele present in at least three reads between the individuals) were also validated by Sanger sequencing.

According to the publication of 1000 Genome consortium, these nonexome regions have the lowest sequencing coverage (on average x5 times), and thus they have the highest level of sequencing errors.

Of 25,217 variants fulfilling this criterion, 24 variants were heterozygous in at least three (out of six) re-sequenced FH1-carriers (accounting for low sequence coverage and e.g., under-calling of heterozygous genotypes) (Additional file 9).

We observed that regions with low sequence coverage occur in close proximity to low-complexity DNA.

Deviations due to low sequence coverage will not be corrected by this method.

Twelve regions of the P-SS2 genome that represented areas of high and low sequence coverage were interrogated (Figure S1).

The remaining sequence gaps and low sequence coverage areas were resolved manually using a combination of primer walking, PCR and transposon-mediated sequencing.

Consed was used to visualize and validate the final assembly, and to design PCR primers for filling gaps and augmenting regions of low sequence coverage [47].