Sentence examples for lowest potency from inspiring English sources

CP-99,994 had the lowest potency with significant inhibition at an oral dose of 30 mg/kg.

4 h after drug administration, compounds 1, 6, 8, 9, and 13 18 exhibited remarkable and significant activity (51.67 67.20%) compared to indomethacin (85.70%); a moderate effect was observed for compounds 3 5, 7 and 11 (32.81–46.66%), and compounds 2, 10, 12 and 19 showed the lowest potency (Fig. 1).

The ortho-hydroxylated PCB had the lowest potency among the four OH-PCBs studied.

The compounds developed here had the lowest potency against HSV-2 Pr, with IC50 values ranging from ∼37 to 94 μM.

Seven of the pyrethroids tested increased sodium influx in a dose-dependent manner (from highest to lowest potency: deltamethrin, S-bioallethrin, β-cyfluthrin, λ-cyhalothrin, esfenvalerate, telfluthrin, fenpropathrin).

PFOS has the highest inhibitory effect on the binding affinity of the liver fatty acid binding protein for liver FAs whereas PFOA had the lowest potency among the examined PFCs (Luebker et al. 2002).

15a showed low potency in induction of apoptosis.

Therapy of pulmonary hypertension is limited by the low potency and adverse effects of current pulmonary vasodilators.

However, these low potency compositions rapidly precipitated leading to significantly lower AUCs (p < 0.05).

However, due to low potency or poor druggability, none of its inhibitors are clinically available.

Current PARP inhibitors are generally non-selective, and inhibit the mono-ADP-ribosyltransferases with low potency.