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Therefore, the putative presence of genomic regulatory blocks at 3R may explain the apparent contradiction of lowest gene density coupled with lowest Ty3/gypsy insertions.
Contrary to expectation, the non-pericentromeric euchromatin (NPE) of 3R presents the lowest density of Ty3/gypsy insertions despite having the lowest gene density (Table 3).
This is the lowest gene density yet observed among chlorophyte cpDNAs.
Among chromosome arms, the lowest gene density of 9.42 per Mb was found in the q arm of the homomorphic sex-determining chromosome.
Among the four species, the D. mojavensis F element has the lowest gene density (48 genes/Mb compared with 60 66 genes/Mb in the other F elements).
Similarly, in chromosome 5 of C. melo species, the lowest gene density (Fig. 6b) was detected at the pericentromeric heterochromatin region with strong sGISH signals.
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Chromosome 5 is one of the largest human chromosomes and contains numerous intrachromosomal duplications, yet it has one of the lowest gene densities.
These bands showed the highest and the lowest gene densities, respectively, as well as a number of other distinct features.
Interestingly, chromosome arm 1q, which is homologous to the 2R arm of An. gambiae, has by contrast the lowest gene densities and the highest coverage of tandem repeats in Ae. aegypti.
These subgenomes have been reconstructed by grouping the 24 conserved blocks: the least fractionated subgenome (LF), with the highest gene densities; the medium fractionated subgenome (MF1), with moderate gene densities; and the most fractionated subgenome (MF2), with the lowest gene densities [ 3, 4].
Gene density distribution in humans differs essentially from that of fungi, archaea and bacteria, showing areas of high and low gene density [56].
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