The condition with the most collagen, 25%, exhibited the lowest expression of macrophage markers but also resulted in a thicker intimal layer.
The lowest expression of LC3 II protein was observed in melanoma metastases (53.3% of cases) (P <.05); LC3 II protein overexpression was, however, found in several nonbenign lesions, with the highest percentage (45.5%) in radial growth phase melanomas.
Interestingly, we found the lowest expression of NKp30L and NKp44L on these cells, consistent with other reports [31], [33].
The lowest expression of MnGus was at the perinucleolus (PN) stage when the number of previtellogenic oocytes increased.
The lowest expression of LHR was obtained in fish exposed to EE2, or DEHP being the lowest doses (0.02 and 0.2 µg/l) the most injurious (Figure 3B).
The tissue with lowest expression of MBD5 or MBD6 was arbitrarily set to a value of 1, to permit easier comparisons.
The lowest expression of the tested cytokines in the visceral WAT of ApoE−/− PGC-1α−/− mice was observed for IL-18.
The lowest expression of mPR was obtained in fish exposed to EE2, or DEHP at doses of 0.02 and 0.2 µg/l.
Mice that had the lowest expression of foxp3-GFP within intra-tumor Tregs had the greatest corresponding CD8 Treg ratio, while those with normal expression had ratios similar to those seen in IgG-treated mice (Figure 5C).
Moreover, individual LV samples with the highest or lowest expression of each of these genes mapped to the predicted methylation state in their correlation between methylation and expression independently of disease state.
We do not believe that this is simply due to the low amount of Flag-Sox2-HMG present in the co-immunoprecipitation eluate, given the large amount of Sall4 co-immunoprecipitated by Flag-Sox2-ΔHMG, which had the lowest expression of the Sox2 constructs in this experiment.
