Sentence examples for lowest efficacious dose from inspiring English sources

To determine the lowest efficacious dose of oral meloxicam for relieving pain in cats with a sodium urate (SU -induced acute inflammatory SU -induced

Most experts currently recommend continuation of mTOR inhibitors at the lowest efficacious dose.

Consequently, ASA guidelines advocate that the lowest efficacious dose of neuraxial opioids be used to minimize this risk [ 14].

CGRP RO was evaluated in healthy subjects (n=3) at the lowest clinically efficacious dose (140 mg, PO) of telcagepant ~2h after dosing, coinciding with the time point of efficacy evaluation in clinical migraine studies.

We compared the toxicity of our FKDC therapeutic regimen with toxicity seen using the lowest therapeutically efficacious dose (2 mg/kg) of systemic FK506.

To address the reviewers' question, we examined the toxicity of our FKDC therapeutic regimen with toxicity seen using the lowest therapeutically efficacious dose (2 mg/kg) of systemic FK506.

The co-administration of a low but efficacious dose of the compound with doxorubicin is well tolerated in mice.

Follow-up preclinical studies will have to monitor appropriate dosing regimens in order to establish the lowest possible efficacious doses while attempting to prevent unwanted offside effects.

Overall, the efficacy and side effect profiles of the two compounds exhibited differentiation at low to mid doses (0.03 0.1 mg ciclesonide, 0.01 0.03 mg fluticasone), while this differentiation diminished at the maximum efficacious dose (0.3 mg ciclesonide, 0.1 mg fluticasone), likely due to overdosing in this model.

However, this differentiation diminishes at the maximum efficacious dose.

Such a disconnect makes predicting PK/PD and efficacious dose in humans very difficult.