Sentence examples for lowest dose tested from inspiring English sources

In the absence of an experimentally determined NOAEL, the quantity lowest-observed-adverse-effect level (LOAEL) can be used as is the lowest dose tested for a potential hazard.

All the derivatives showed protection against the maximal electroshock seizure test (MES test) in mice at the lowest dose tested (30 mg/kg) but they did not show significant protection against the chemical induced convulsion by pentylenetetrazole.

Optimal doses of 1A, 2A, 11C, 13D, and 15D, as indicated by the greatest increases in NDFD at the lowest dose tested, were 2×, 2×, 1×, 0.5×, and 0.5×, respectively.

There was no dose response as it appeared as if the lowest dose tested gave the maximum effect.

Expression of Klk4 decreased significantly at the lowest dose tested (50 ppm, p<0.05) and the expression of Amtn decreased significantly at 100 ppm F−.

The induction of p38 oxidation by PGJ2 was dose responsive (Figure 5A), with distinct oxidation detected with PROP at the lowest dose tested, 25 µM.

NOAELs were not identifiable for these sensitive end points because effects were reported at the lowest doses tested.

Shedding of soluble TNF receptors was not detected at the lowest doses tested (⩽0.8  μg m−2), while thereafter increased proportionally with dose up to a plateau observed at ⩾25  μg m−2.

Unexpectedly, the effects on CaOV-3 were the exact opposite as the cells become more sensitive to platinum with 20-25% more cell death even at the lowest doses tested.

But it is very interesting that, despite the low concentration of RA in the lowest HRAM dose tested, we still saw marked inhibition of LPS-induced PGE2 by HRAM.

The lowest E2 dose tested, 400 pg/egg (40 ng/kg), sex reversed 14.4% of the animals, demonstrating very low dose sensitivity.