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Bases that fail to reach this threshold are called 'N.' The optimum total threshold quality score is determined empirically to be 12, which yields the highest base-call rate with the lowest discrepancy between genotypes for replicate samples.
They explore the distribution of the impurity atoms by calculating the discrepancy factor (eq 41) around each unrelaxed impurity atom when placed on either the Li or Nb site and assume that the site with the lowest discrepancy factor is the likely site for the impurity as described in more detail in section 8.3.
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Although model 2 had the lowest discrepancies for fasts up to 50 days, between 50 and 200 days it was more discrepant than model 3. On average, model 3 provided the least discrepant predictions over the widest duration of fasts.
The systematic review found rather low discrepancy rates.
This inequality states that sequences with low discrepancy lead to low error [9].
This is the first sequence by which low discrepancy was formed.
Reference [9] presented modified variants of PSO using different low discrepancy sequences.
For high dimensional uniform designs we apply the threshold accepting heuristic for finding low discrepancy designs.
Low discrepancy Quasi Monte Carlo methods are the most suitable initial sampling designs.
Low discrepancy designs are those whose empirical distribution functions match a fixed target distribution.
Therefore, the weighting factor should be adjusted to realize two conflicting goals: fast convergence and low discrepancy error.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com