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Even at the lowest detectable levels of exposure, we could detect changes in gene expression within the cells lining the airways," says coauthor Ronald Crystal, head of pulmonary and critical care medicine at New York-Presbyterian/Weill Cornell Medical Center.
On the reclamation site, almost all individuals in the infected component (22%) of the July 2009 sample had the lowest detectable levels of Bd.
That said, we have demonstrated that even expression of these chimeric proteins at the lowest detectable levels is sufficient to induce mitochondrial dysfunction; thus, it is likely that any endogenous expression of these proteins would be deleterious.
But considering there is believed to be no safe level of lead exposure, the Campaign for Safe Cosmetics would like to see guidelines for lead in lipstick set to correspond with the lowest detectable levels found in laboratory tests (less than 0.02 ppm), says spokeswoman Margie Kelly.
Now a professor at the University of Pittsburgh Medical Center, Needleman was an assistant professor at Harvard Medical School when he used blood lead as a biomarker to show that even at the lowest detectable levels, lead could impair a child's IQ.
A recent study quantified levels of PBDEs in commonly consumed foods in the United States and showed the highest levels of PBDEs in butter and fish, and the lowest detectable levels in other liquid dairy products (milk and yogurt) and vegetables [ 59].
Similar(6)
The lowest detectable level that can be distinguished from the zero standard is 0.6 ng/ml.
The lowest detectable level that could be distinguished from the zero standard was 0.31 fmol/tube.
The lowest detectable level was 0.02 mg/L.
The lowest detectable level was 100 pg/mL.
The cell line was clonally derived to express at p65-DsRed at lowest detectable level to preserve near endogenous expression.
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