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Table 3 shows that 2× more SWs than controls had neutralizing antibodies against pandemic (H1N1) 2009 virus for the lowest cutoff value (p = 0.001).
The threshold value of 15% was found to be the lowest cutoff value that did not include pixels in the contra lateral non ischemic hemisphere [ 18].
C-terminal FGF23 levels were measured from plasma samples by enzyme-linked immunosorbent assay (lowest cutoff value of 3 relative units (RU /ml, highest cutoff value of 2,000 RU/ml; Immutopics International, San Clemente, CA, USA).
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Sensitivities at the lowest cutoff values, 20 50 ng/mL, range from 66%to88%8% for CRC detection [ 34– 36], while sensitivity at the highest cutoff value of 300 ng/mL is 56% for CRC [ 37].
This dependency is not so outspoken for the PM metric, except in the case when a very bad model is combined with a low cutoff value (χ = 1%).
Finally, we also checked current distributions for a very low cutoff value of Z = 1.96.
First, we retained a low cutoff value for PCT assay (0.2 μg/l).
The relatively high proportion of patients with depressive symptoms in our study might be explained by the low cutoff value.
This is strongly supported by the high seropositivity rate in healthy individuals if the low cutoff value is chosen.
This gave an accurate classification in 79.4% of patients compared with 72.5% if the low cutoff value was used.
However, a low cutoff value in individual gene analyses may result in many genes with moderate but meaningful changes in expression being missed.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com