Sentence examples for lowest coverage depth from inspiring English sources
Since in general the cost of correcting the reads in terms of running time and memory usage is significant, in the following we present the results obtained using the set of long reads non-corrected LR-E with the lowest coverage depth, x20.
While Y sequences often do have low coverage depth, it is often not sufficient to classify a sequence as Y-linked solely by low coverage depth.
But in a low coverage depth situation, the performances of SWA are a little down.
So the appropriate sliding window can improve the performances of SWA and compensate the read loss of low coverage depth.
The coverage depth distribution shows that the fraction of uncovered bases at low coverage depth increased dramatically in all samples that had undergone WGA.
Although most of these tumors were sequenced at low coverage depth, we identified 2183 and 3138 mutated genes from respectively the CRC and EM tumor data sets.
Using a large k-mer has the advantage of resolving more repeat regions; whereas, use of small k-mers is advantageous for assembling low coverage depth and removing sequencing errors.
These data with low coverage depth on the HLA region might only be suitable for an alignment-based approach instead of a de novo assembly-based approach such as HLAreporter.
Mis-assemblies of the reference genome, and allelic differences between the reference genome and the short-read sequence data could lead to low coverage depth causing errant classification of Y-linkage.
These are divided into tests of copy number variation (which platform, if performed); single genes tested with negative and inconclusive results, with a separate box for each gene, so that this is searchable; whole exome sequencing (presumably with low coverage depth and certainly no conclusive results); and other important tests.
Nonetheless, it is clear that under some circumstances variant calling is significantly impacted by post-mortem damage patterns and low DNA availability typical of aDNA samples, particularly so for accuracy in SNP calls at high levels of damage, and for overall indel and SNP recovery at low coverage depths.
