"This is a very low conception of what being human is," he said.
3 6 Antioestrogenic effects of CC on the endometrium and cervix mucus are thought to cause the low conception rate.
Hence, low conception rates could be directly linked to inflammation induced, altered cellular plasticity, in uterine endometrial tissues.
This study strictly examines gene expression between high and low conception rate animals without influence from any exogenous metabolites, either dietary or pharmaceutical.
Domestic buffalo are considered to have low reproductive efficiency, characterised by late attainment of puberty and maturity, seasonality of calving, long postpartum anoestrus, poor expression of oestrus signs, low conception rate and long calving intervals [ 1, 2].
As high progesterone levels are positively associated with embryo survival [ 60, 93], it is therefore possible that the LF animals are experiencing low local progesterone concentrations and ultimately, this could be contributing to their low conception rates.
However, in the bitch herpesvirus infection has been associated with reproductive problems, such as low conception rate, fetal resorption, abortion, stillborn or weak puppies and small litter size both in experimental [ 8, 9] and epidemiological studies [ 10- 12].
It was essential to use RNA from all endometrial cell types as it is not apparent, as of yet, whether or which individual endometrial cell types are contributing to low conception rates in cattle.
Note, however, that the result is not just due to very low second conception risks in cohabitation; Italy and Lithuania also have low cohabiting conception risks, but the interaction term between these countries and cohabitation is not significant, indicating that the relationship between union status and fertility is the same as in France.
