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Here we address the target engagement question: what is the minimum extent of Aβ lowering sufficient for significant cognitive benefit in AD patients?
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As a result, smaller unicells will be able to survive whereas large carnivores are unable to find sufficient prey, lowering the average size and the prey/predator ratio.
While stopping unwanted/unacceptable BP lowering medication is usually sufficient to eliminate these perceptions, renal denervation while generally safe is irreversible.
However it remains unproven - and even doubtful [ 17] - that all of these current recommendations are sufficient for lowering postmenopausal breast cancer risk.
It may therefore be the case that if antisense oligonucleotides are only able to target the cortex this may cause sufficient huntingtin lowering to preserve structural network integrity and prevent conversion to manifest Huntington's disease.
This study quantifies the current levels of data quality and evaluates Lot Quality Assurance Sampling (LQAS) as a tool to prioritize sites with low data quality, thus lowering costs while maintaining sufficient quality for program monitoring and patient care.
Nevertheless, some studies have shown that patients on powerful new antiviral therapies appear able to regenerate some of these cells once viral burdens have been lowered for a sufficient amount of time--leading researchers to wonder about the source of these new T cells.
Specific comments – "motivates me to lower my cholesterol", "sufficient information", "easy to understand", "clear language", "options are clear and in a logical order" and "providing a variety of options is more motivating than someone just telling me what to do".
In the previous section we proposed two algorithms to tackle the memory requirements of the BBA when dealing with large image sets: the solution is to reduce the amount of processed data to a lower, but sufficient, number of tie-points.
In the first Kinetograph application, Edison stated, "I have been able to take with a single camera and a tape-film as many as forty-six pertographsecondsecond...but I do not wish to limit the scope of my invention to this high rate of speed...since with some subjects a speed as low as thirty pictures per second or even lower is sufficient".
While estimates vary, an increase of 10% CFTR channel activity on the plasma membrane has been predicted to be the lower limit sufficient to relieve the CF clinical phenotype [44].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com