Exact(1)
The (intensity weighted) particle size increased from 281 nm for the drug free emulsion to 550 nm following a loading of 1 g L−1 of halofantrine, indicative of a lowering in stability and this was reflected in a shorter shelf life.
Similar(59)
Thus, it is expected that the decrease of soluble alginate on Hydrogum 5 will cause a lower alteration in stability because a lower weight percentage gel is invariably subject to fewer changes in dimension by syneresis, evaporation, and imbibition of water.
Therefore, high content of Lysine, Asparagine, Isoleucine, Alanine, Arginine, Glycine and Proline according to Bernardi [ 57] are linked to lower protein stability in human genome.
These alterations of the callus composition resulted in lowered biomechanical stability with a higher flexibility of bone within the callus after 28 days of healing.
Overall, the biodistribution and PET scanning data point to significantly lower in vivo stability of Zr-YM103-trastuzumab compared to Zr-DFO-trastuzumab with respect to dissociation of the Zr4+ metal complex.
This increased O-methylation rate is caused by the fluorine atom in position 5 in direct vicinity to the hydroxyl group in position 4 [ 35] and results in a significantly lower in vivo stability of 5-[F]F-DOPA ([ 18 F] 4, Figure 2).
The secretion process (particularly post-translational modifications) in insect cells might lower the stability and thus lead to difficulties in maintaining the correct conformation at low pH during purification.
The TLR2 data was comparable to the ALU J data, although because the starting copy was much lower, any decrease in stability generally led to complete loss of signal (data not shown).
However, Figure 3 also shows a slightly higher background uptake for 68 Ga-TRAP MDP 3, Ga-TRAP MDP 3aused by partial decomostxation in vivo due to likelycausedx stabylity.
For E. coli, we generally considered mRNA stability for the first 30 bases of a coding sequence, as Gu et al. (2010) had previously shown that lowered stability occurred primarily in this region.
Our results further verify inefficiency of Na2Ita in lowering particle size and stability to such a degree that some coagulated particles were seen as the concentration of Na2Ita increased to 10 mol% (Fig. 7d).
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