Sentence examples for lowering efficacy from inspiring English sources

In diabetic (db/db) mice, compound (S -5b S -5bd good glucoshowederingoodficacy and favorable pharmacokinetic properties.

However, the recent randomized sham-controlled Symplicity HTN-3 trial did not show a difference in blood pressure (BP) lowering efficacy between RDN and sham treatment [4].

Our data suggest that the lack of BP lowering efficacy in the sham-controlled Simplicity HTN-3 study may be related to lack of procedural effectiveness.

Oral administration of Compound 1 at doses as low as 0.03 mg/kg led to robust blood glucose lowering efficacy in 3 week high fat diet-fed mice.

They not only respond in a human-like manner to pharmaceutical interventions with respect to lipid lowering efficacy [31], [32] but also respond to HDL modulating therapy.

53 This justifies the use of atorvastatin in alternate-day dosage as it maintains its cholesterol lowering efficacy for longer.

Their blood glucose-lowering efficacy is similar to that of other antihyperglycemic drugs besides insulin (43, 44) PPAR-γ therapy over time has some safety concerns.

Furthermore statin therapy in HIV-infected patients has a lipid-lowering efficacy lower than expected, thus patients may require high doses or additional cholesterol-lowering agents [ 8].

In addition to robust IOP-lowering efficacy, fixed-combination therapies provide multiple benefits versus treatment with the corresponding separate medications [ 7].

Olmesartan medoxomil is an ARB that is characterized by strong blood pressure-lowering efficacy with a fast onset, prolonged duration of action and good tolerability.

Mice lacking DPP-4 entirely were found to be resistant to high-fat diet- induced obesity and have lower insulin concentrations with a greater glucose-lowering efficacy.