Sentence examples for lowering compound from inspiring English sources

Simvastatin is an important cholesterol lowering compound and is currently synthesized from the natural product lovastatin via multistep chemical synthesis.

Interestingly, although atorvastatin is a more potent cholesterol lowering compound than simvastatin [41], in our study both simvastatin and atorvastatin showed an equal association with low values of periodontal inflammatory burden index PIBI.

The effect of screen-selected cholesterol lowering compounds on the major sterol pathways was studied in CT60 mutant CHO cells lacking NPC1 protein.

The cholesterol lowering compounds known as statins were discovered through isolation of microbial agents capable of disrupting HMG-CoA (3-hydroxy-3-methylglutaryl-coenzyme A) reductase (HMGCR) activity.

Daming capsule (DMC), a traditional Chinese formula, has a lipid-modulating action with reduced adverse side effects as compared with other lipid lowering compounds.

To alleviate this problem steps occurring after the committing reaction of steroid biosynthesis, i.e. the synthesis of squalene from farnesylpyrophosphate catalyzed by squalene synthase (EC 2.5.1.21) might be potentially useful targets for the design of new cholesterol lowering compounds.

Natural rubber and styrene/butadiene rubber have been blended for a long time for many purposes such as lowering the compound cost [4, 5].

Lowering the compound's concentrations obviously leads to lower precursor intensities and hence, less fragment signals, which can be automatically recognized by the software (Table S-2).

A number of therapies for complex diseases use combinations of drugs that allow targeting of multiple mechanisms and allow therapeutic efficacy at lower compound concentrations, limiting toxicity of single agents.

For all proteins evaluated, the observed expression changes occurred at lower compound concentrations in parental cells compared to resistant cells.

Nevertheless, some structure-specific interactions observed among native N-carbamoylase molecules may promote multilayer adsorption and thus lead to a much higher adsorption capacity, 715 nmol/g gel and a lower compounded binding affinity, 0.42 μM−1.