Sentence examples for lowering affinity for from inspiring English sources

Arg112 and Lys145 may be located in the HS-binding interface based on their interaction with sulfate ions and their mutation to histidine or glutamine could have an effect of lowering affinity for HS.

Mutants displaying similar or higher binding affinities to DR4, together with a lowered affinity for DR5, were characterized.

In FcγRIIIA, a valine for phenylalanine substitution (V176F, rs396991) lowers affinity for IgG1 and IgG3, and prevents binding to IgG4 (12).

This decrease may be attributed to its ≈ 10-fold lower affinity for hsst5.

Unexpectedly, the tri-amine grafted samples exhibited lower affinity for both metal cations.

Pyrrolidone 15 was found to exhibit reasonable affinity for PKCδ, with lower affinity for the other isozymes tested.

Subtle changes in cyclohexane stereochemistry and removal of functional groups led to analogues with lower affinity for the MC receptors.

Subjects were examined using SPECT with the ligand [123I]FP-CIT, which has a high affinity for the dopamine transporter and somewhat lower affinity for the SERT.

TypeI binding sites show high affinity for PACAP38 and PACAP27 (Kd = approximately 0.5 nM) and much lower affinity for VIP (Kd > 500 nM) [5 8].

Boggy soil and yellow brown soil showed higher affinities for Cd2+ and Zn2+, respectively, while paddy soil has lower affinity for both cations.

These results support the previously made hypothesis (Baroi et al. 2015a) that C. tyrobutyricum has a lower affinity for xylose than for glucose.