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The Turmeric rhizomes have been reported to possess antidiabetic properties as its alcohol extract possesses active constituents showing blood glucose lowering activity in alloxan induced diabetic rats [ 18].
Pterostilbene from Pterocarpus marsupium, resveratrol from red grapes have been reported to activate PPAR alpha and posess glucose and lipid lowering activity [ 48].
Significant amount of blood glucose lowering activity was observed for the ethanolic leaf extract.
A preliminary in vivo screening indicates that 1b and 2a have moderate triglyceride lowering activity.
In addition, the minor monomers also exhibited moderate glucose lowering activity.
Some of the synthesized compounds showed promising in vivo anti-hyperglycemic as well as moderate lipid lowering activity.
Similar(29)
The IAT SIRT1 activator SRT2104 demonstrated significant glucose-lowering activity in both the ob/ob and dietary obesity mouse models.
Glucagon-like peptide-1 (GLP-1) is an endogenous insulinotropic hormone with wonderful glucose-lowering activity.
Exendin-4 inspired modification resulted in peptide 1b with enhanced glucose-lowering activity.
The lipid-lowering activity was evaluated using a cell-based screening system.
In conclusion, the present study demonstrates a marked cholesterol-lowering activity of proteins from L. angustifolius in rats.
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