Sentence examples for lowered efficacy from inspiring English sources

However, evaluation of the total population in this study did not show more than a trend to a lowered efficacy of clopidogrel.

Again, the AR initiation efficacy of poly(Fuc 100 is lower than for poly(Man 100 and poly(GlcNAc 100, consistent with the lowered efficacy of poly(Fuc 10.

Authors' response: Intracellular genomes encounter elevated genetic drift resulting from relaxed selection on many genes and from radical change in population structure that results in lowered efficacy of selection on genes [ 66- 68].

Several mechanisms could contribute to the lowered efficacy of macroscopic activation, including a decreased affinity for cGMP, alterations in coupling of cGMP binding to channel opening, decreased open probability or single channel conductance, the loss of modulating protein/signaling interactions, and others; these are interesting questions to pursue in future studies.

In diabetic (db/db) mice, compound (S -5b S -5bd good glucoshowederingoodficacy and favorable pharmacokinetic properties.

However, the recent randomized sham-controlled Symplicity HTN-3 trial did not show a difference in blood pressure (BP) lowering efficacy between RDN and sham treatment [4].

Our data suggest that the lack of BP lowering efficacy in the sham-controlled Simplicity HTN-3 study may be related to lack of procedural effectiveness.

Oral administration of Compound 1 at doses as low as 0.03 mg/kg led to robust blood glucose lowering efficacy in 3 week high fat diet-fed mice.

They not only respond in a human-like manner to pharmaceutical interventions with respect to lipid lowering efficacy [31], [32] but also respond to HDL modulating therapy.

Also, the average time on risperidone decreases as patients will switch treatment earlier due to lower efficacy.

53 This justifies the use of atorvastatin in alternate-day dosage as it maintains its cholesterol lowering efficacy for longer.